GGsTop, a novel and specific {gamma}-glutamyl transpeptidase inhibitor, protects hepatic ischemia-reperfusion injury in rats

In conclusion, treatment with GGsTop increased glutathione levels and prevented formation of free radicals in the hepatic tissue that led to decreased IR-induced liver injury. GGsTop could be used as a pharmacological agent to prevent IR-induced liver injury and the related adverse events.

Source: AJP: Gastrointestinal and Liver Physiology - August 8, 2016 Category: Gastroenterology Authors: Tamura, K., Hayashi, N., George, J., Toshikuni, N., Arisawa, T., Hiratake, J., Tsuchishima, M., Tsutsumi, M. Tags: LIVER AND BILIARY TRACT PHYSIOLOGY/PATHOPHYSIOLOGY Source Type: research