Optimal initial state for fast parameter estimation in nonlinear dynamical systems

• A criterion to design optimal initial state in a bounded-error context is given.• A study to optimize the sampling period is given.• Some comparative results highlighted the proposed approach are developped.• This methodology is applied to a model of glucose-oxydase pharmacokinetics.
Source: Computer Methods and Programs in Biomedicine - Category: Bioinformatics Authors: Source Type: research