Association Between Circulating Osteogenic Progenitor Cells and Disability and Frailty in Older Persons: The Nepean Osteoporosis and Frailty Study

In conclusion, COP cells in the circulation decrease with age. Lower percentages of COP cells in late life are associated with prevalent frailty and disability. Further longitudinal studies are needed to understand COP cells as a risk stratifier, biomarker, or therapeutic target and to predict disability in frail older persons.

Source: Journals of Gerontology Series A: Biological Sciences and Medical Sciences - August 8, 2016 Category: Geriatrics Authors: Gunawardene, P., Bermeo, S., Vidal, C., Al-Saedi, A., Chung, P., Boersma, D., Phu, S., Pokorski, I., Suriyaarachchi, P., Demontiero, O., Duque, G. Tags: Original Article Source Type: research