Fenretinide: A Potential Treatment for Endometriosis

Conclusions: Fenretinide increases STRA6 expression thereby potentially reversing the pathological loss of retinoid availability. Treatment with this compound induces apoptosis. In vivo treatments decrease lesion volume. Targeting the RA signaling pathway may be a promising novel treatment for women with endometriosis.

http://rsx.sagepub.com/cgi/content/abstract/23/9/1139?rss=1

Source: Reproductive Sciences - August 8, 2016 Category: Reproduction Medicine Authors: Pavone, M. E., Malpani, S. S., Dyson, M., Kim, J. J., Bulun, S. E. Tags: Original Articles Source Type: research