The story of poorly differentiated thyroid carcinoma: From Langhans ’ description to the Turin proposal via Juan Rosai

Rosai, reinterpreting Langhans ’ “proliferating goiter,” adopted the term “poorly differentiated carcinoma” for a specific thyroid tumor with insular features 30 years ago. This tumor type is only one of those approached by Dr. Rosai in the thyroid field (a PubMed search as of August 31, 2015 on “Rosai& thyroid ” disclosed 73 articles), but seems the most innovative and representative of his heavy contribution to thyroid tumor classification. The diagnostic problems associated with PDTC recognition date back a long time, with a still ongoing debate on the nature of PDTC, its morphological diagnostic feat ures, its clinical significance, and its optimal therapeutic approach.
Source: Seminars in Diagnostic Pathology - Category: Pathology Authors: Source Type: research