Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction
Conclusion:
Patients with diabetes and macrovascular complications have increased amino acid ratios reflecting a shift in arginine metabolism due to arginase activation. These changes are inversely related to endothelial function supporting that arginase activity contributes to endothelial dysfunction.
Source: Diabetes and Vascular Disease Research - Category: Endocrinology Authors: Kövamees, O., Shemyakin, A., Pernow, J. Tags: Original Articles Source Type: research