An observational study of extending FOLFOX chemotherapy, lengthening the interval between radiotherapy and surgery, and enhancing pathological complete response rates in rectal cancer patients following preoperative chemoradiotherapy

Conclusion:
The intensified multimodality therapy was well tolerated in our cohort and resulted in a considerably high pathologic complete response rate. Regardless of favorable short-term clinical outcomes, long-term oncologic outcomes will be closely monitored among the patients with a pathologic complete response.

Source: Therapeutic Advances in Gastroenterology - August 7, 2016 Category: Gastroenterology Authors: Huang, C.-M., Huang, M.-Y., Tsai, H.-L., Huang, C.-W., Ma, C.-J., Yeh, Y.-S., Juo, S.-H., Huang, C.-J., Wang, J.-Y. Tags: Original Research Source Type: research