Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma: A case report and literature review

Neurolymphomatosis (NL) has been used to describe the circumstance when malignant lymphoid cells invade the peripheral and/or cranial nerves and nerve roots [1,2]. Although rare, there is a predilection of the sciatic nerve when mononeuropathy is present [3,4]. The exact mechanism of the exclusive involvement of the sciatic nerve is still unknown. Generally, clinical symptoms of sciatic neuropathy due to lymphoma include pain, numbness, and weakness of the involved lower extremity, which are non-specific and challenging to diagnose.
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research