Human papillomavirus positive oropharyngeal cancer: The general information

Publication date: Available online 6 August 2016 Source:Egyptian Journal of Ear, Nose, Throat and Allied Sciences Author(s): Omer Tarık Selcuk Oropharyngeal squamous cell cancer (OPSCC) and especially Human papilloma virus positive (HPV+) OPSCC incidence is increasing worldwide over the last decades while the incidence of overall head and neck squamous cancers has declined in developed countries. HPV+OPSCC has favorable prognosis and is seen in younger patients with lower exposure to tobacco and alcohol. This review will summarize our current understanding about HPV+OPSCC and clinical differences comparing with HPV−OPSCC including current therapy approaches and describe the clinical importance of determining the HPV status.
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - Category: ENT & OMF Source Type: research