Risk of individual malignant neoplasms in patients with sickle cell disease: English national record linkage study

Conclusions The risk of some malignancies may be raised in patients with sickle cell disease. However, this study was based on administrative data without the scope to validate these against patients’ full clinical records. Our findings need confirmation or refutation. If confirmed, work to elucidate, at the genetic and molecular level, why people with sickle cell disease have elevated risks of individual cancers might make contributions to the fundamental understanding of carcinogenesis.
Source: JRSM - Category: UK Health Authors: Tags: Research Source Type: research