Neuroendocrine Carcinoma of the Cervix: Review of a Series of Cases and Correlation With Outcome

Conclusions. Histological review of a series of NECs has shown significantly reduced survival in those patients with confirmed NEC in comparison with those patients where a diagnosis of NEC was not confirmed. We propose morphological and immunohistochemical criteria for the diagnosis of cervical NEC; and discourage unqualified use of the term "small cell carcinoma" as this does not accurately convey the diagnosis of SCNEC. We urge pathologists to use the 2014 World Health Organization classification when reporting these tumors.

Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Ganesan, R., Hirschowitz, L., Dawson, P., Askew, S., Pearmain, P., Jones, P. W., Singh, K., Chan, K. K., Moss, E. L. Tags: Original Articles Source Type: research