Cranberry extract attenuates hepatic inflammation in high fat-fed obese mice

Cranberry (Vaccinium macrocarpon) consumption has been associated with health beneficial effects. Non-alcoholic fatty liver disease (NAFLD) is a co-morbidity of obesity. In the present study, we investigated the effect of a polyphenol-rich cranberry extract (CBE) on hepatic inflammation in high fat-fed obese C57BL/6J mice. Following dietary treatment with 0.8% CBE for 10weeks, we observed no change in body weight or visceral fat mass in CBE supplemented mice compared to high fat-fed control mice.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research