Antibacterial and biological properties of biofunctionalized nanocomposites on titanium for implant application
In this study, we demonstrate a simple one-step, water-based procedure for the fabrication of biofunctionalized nanocomposites on titanium for implant application. The formation of biofunctionalized silver nanoparticles with varied biomolecule templates is confirmed by Fourier-transform infrared spectroscopic, contact angle, field-emission scanning electron microscopy, and inductively coupled plasma atomic emission spectrometry analysis. Antibacterial properties of the specimens were determined by challenging them against Staphylococcus aureus. The Ag-incorporated titanium shows excellent antibacterial ability against planktonic bacteria in the suspension and ability to prevent bacterial adhesion. The specimens with optimized biomolecule/silver ratio promote osteoblast differentiation. These biofunctionalized silver nanoparticles-doped titanium specimens, with improved antibacterial activity while maintaining healthy osteoblast cellular activity, have promising application in orthopedics, dentistry, and other biomedical devices.
Source: Journal of Biomaterials Applications - Category: Materials Science Authors: Li, P., Tong, Z., Huo, L., Yang, F., Su, W. Tags: Functional Biomaterials Surfaces Source Type: research
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