MicroRNA target for MACC1 and CYR61 to inhibit tumor growth in mice with colorectal cancer

In conclusion, the abilities of apoptosis, metastasis, and invasion in CRC tumor cells were significantly suppressed by miRNA-100 and miRNA-143 targeting CYR61 and MACC1, respectively. As a result, CYR61 and MACC1 may serve as potential targets for gene therapy in human CRC treatments.
Source: Tumor Biology - Category: Cancer & Oncology Source Type: research