Angiotensin II Type 1 receptor (AGTR1) gene polymorphisms are associated with vascular manifestations in patients with systemic sclerosis (SSc)
Conclusions:
This is the first report of the association of these polymorphisms with vasculopathy in Mexican admixed SSc patients. Our findings suggested that the angiotensin II Type 1 receptor genotype may influence the clinical expression of vasculopathy in these patients. Functional analyses should follow.
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - Category: Biomedical Science Authors: Rodriguez-Reyna, T. S., Nunez-Alvarez, C., Cruz-Lagunas, A., Posadas-Sanchez, R., Perez-Hernandez, N., Jimenez-Alvarez, L., Ramirez-Martinez, G., Granados, J., Vargas-Alarcon, G., Zuniga, J. Tags: Original Article Source Type: research