Daily sesame oil supplementation attenuates local renin-angiotensin system via inhibiting MAPKs activation and oxidative stress in cardiac hypertrophy

We examined the protective role of sesame oil on RAS-mediated MAPKs activation and oxidative stress in rats. We induced LVH using a hypertensive model by subcutaneously injecting deoxycorticosterone acetate (DOCA; 15 mg/ml/kg in mineral oil; twice weekly for 5 weeks) and supplementing with 1% sodium chloride drinking water (DOCA/salt) to uni-nephrectomized rats.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research