Regenerated cellulose/polypyrrole/silver nanoparticles/ionic liquid composite films for potential wound healing applications

Publication date: Available online 2 August 2016 Source:Wound Medicine Author(s): Nargis A. Chowdhury, Ahmed M. Al-Jumaily In this work, regenerated cellulose/polypyrrole/silver nanoparticles (AgNPs)/ionic liquid (IL)-loaded composite films (RC/PPy/Ag/IL) have been synthesized for potential wound healing applications. RC/PPy/Ag nanocomposites were successfully synthesized via in situ chemical oxidation polymerization of pyrrole. The molar ratio of monomer unit to oxidization agent (Silver nitrate) was 1:1. In the reaction between pyrrole and silver nitrate, silver ions oxidize the pyrrole monomer and get reduced and deposited on/into the polypyrrole/regenerated cellulose matrix layer. When IL was in contact with AgNPs, the interface dipole was induced, and high positive charge appeared on the AgNPs surface. Such charged Ag atoms inhibit the growth of gram-positive and gram negative bacteria. The electrical conductivity and strong antimicrobial activity, makes it a suitable candidate in wound healing applications. The RC/PPy-Ag/IL nanocomposite films were characterized using scanning electron microscopy (SEM), and FTIR spectroscopy. The films developed here may have potential applications in wound healing.
Source: Wound Medicine - Category: Journals (General) Source Type: research