The Re-Emergence of Lipoprotein(a) in a Broader Clinical Arena

Lipoprotein(a) [Lp(a)] is a genetic, independent and likely causal risk factor for cardiovascular disease (CVD) and calcific aortic valve stenosis (CAVS). Lp(a) levels are primarily genetically determined and tend to fluctuate only mildly around a pre-determined level. In primary care settings, one Lp(a) measurement can reclassify up to 40% of patients in intermediate risk score categories. In secondary care settings, recent data from the JUPITER and AIM-HIGH trials demonstrate that elevated Lp(a) remains part of the “residual risk” despite achievement of low-density lipoprotein cholesterol levels
Source: Progress in Cardiovascular Diseases - Category: Cardiology Authors: Source Type: research