The Properties of 3 Different Plasma Formulations and Their Effects on Tendinopathic Cells

Conclusion: The main advantages of L-PRP and PRP use, compared with PPP, include their stronger chemotactic and proliferative properties. While PPP and PRP stimulate matrix anabolism, L-PRP is more proinflammatory. Emphasis should be placed on the temporal needs and biological characteristics of injured tendons, and plasma formulations need to be tailored accordingly. Clinical Relevance: Versatile systems allowing the preparation of different plasma formulations, such as PPP, PRP, or L-PRP, can help refine clinical applications by taking advantage of their different biological properties.

http://ajs.sagepub.com/cgi/content/abstract/44/8/1952?rss=1

Source: The American Journal of Sports Medicine - July 31, 2016 Category: Sports Medicine Authors: Rubio-Azpeitia, E., Bilbao, A. M., Sanchez, P., Delgado, D., Andia, I. Tags: Biology of tendon, Cell/Molecular biology, Growth factors/Healing enhancement, Biologic healing enhancement Biology and Translational Research Source Type: research