Cell Mediated Pathologies in Traumatic Orthopaedic Injuries
Physical trauma is one of the most common mechanisms leading to Orthopaedic injury. The trauma and associated inflammatory response initiates the process of tissue regeneration and repair, which includes the recruitment and/or induction of multipotential cells to participate in the process. Too much inflammation can overwhelm this response to cause scarring. While stem cells have been extensively studied as therapy for regenerating functional tissues, concerns of ethics, availability, and ease of clinical utility call for investigation into an alternative source of multipotential cells for potential therapeutic use.
Source: Operative Techniques in Orthopaedics - Category: Orthopaedics Authors: Daniel W. Griffin, Youngmi Ji, Vyomesh Patel, Leon J. Nesti Source Type: research