New polyprenyl phosphate based preparation Fortepren ® as promising cytokine regulationg antiviral remedy

Fortepren ®, a product of the phosphorylation of polyprenols from fir needles (with sodium polyprenyl phosphate being the main active ingredient), belongs to the group of antiviral drugs (group J05AX) with immunomodulating activity [6]. Polyisoprenoid alcohols (PI-OH) include polyprenols (PreOH) and dolichol s (2,3-dihydropolyprenols, DolOH). PI-OH consists of at least 4 isoprene units linked head-to-tail; the molecule of PreOH includes ω-isoprene unit, 2 or 3 trans-isoprene units, a certain number of cis-isoprene units, an α-isoprene unit with cis-configuration and an hydroxyl group at the C-1 carbon atom.
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Tags: Mini review Source Type: research