Local infiltration analgesia in knee and hip arthroplasty efficacy and safety

Conclusion LIA provides good postoperative analgesia which is similar to femoral block after total knee arthroplasty. The plasma concentration of ropivacaine seems to be below toxic levels in most TKA patients. The unbound plasma concentration of ropivacaine in THA seems to be below the toxic level. Implication The use of ketorolac in LIA may not be safer than other routes of administration, and similar restrictions should be applied in patients at risk of developing side effects. Graphical abstract
Source: Scandinavian Journal of Pain - Category: Anesthesiology Source Type: research