T2 relaxometry improves detection of non-sclerotic epileptogenic hippocampus

Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy in adults that can be successfully treated by surgery. Hippocampal sclerosis (HS) is the main pathology of TLE, and is characterized by atrophy and increased T2 signal intensity on magnetic resonance (MR) imaging. Hippocampal volume is correlated with neuron cell count (Briellmann et al., 2002; Van Paesschen et al., 1997). Quantification of hippocampal volume on MR imaging can be useful to detect HS and to identify the epileptogenic side (Jack et al., 1990).

Source: Epilepsy Research - June 24, 2016 Category: Neurology Authors: Shiho Sato, Masaki Iwasaki, Hiroyoshi Suzuki, Shunji Mugikura, Kazutaka Jin, Teiji Tominaga, Kei Takase, Shoki Takahashi, Nobukazu Nakasato Source Type: research