Effectiveness and safety of natalizumab in real-world clinical practice: review of observational studies

Clinical trials have shown that natalizumab is highly effective for treating relapsing forms of multiple sclerosis (MS). The purpose of this analysis was to conduct a targeted review of data from country-specific observational studies and registries of natalizumab-treated patients with relapsing MS in order to more fully investigate the longer-term effectiveness and safety of this disease-modifying therapy in real-world clinical practice settings. A PubMed search was conducted on March 13, 2014, using the terms (natalizumab AND multiple sclerosis) AND (observational OR registry OR post-marketing OR clinical practice).

Source: Clinical Neurology and Neurosurgery - July 12, 2016 Category: Neurosurgery Authors: Vincent van Pesch, Christian J. Sindic, Oscar Fern ández Source Type: research