Automatic counting of fungiform papillae by shape using cross-correlation

The determination of the number of fungiform papillae (FP) on the human tongue is important for taste sensitivity studies. Most of the time, the counting of the FP is done manually. In this paper we propose a novel algorithm to count the FP using shape characteristics measured by cross-correlation. The accuracy of the algorithm is evaluated by counting the FP manually on the same images and then doing a statistical analysis. A Poisson regression model is fitted using maximum likelihood. The result is that the algorithm counts are very similar to the human experts.
Source: Computers in Biology and Medicine - Category: Bioinformatics Authors: Source Type: research