OC10_07 A Close Correlation of Thrombin Receptor Mediated Platelet Aggregation With Clopidogrel Responses

Thrombin, which binds to protease activated receptor (PAR)-1 or 4 of platelet surface, is a more potent agonist of platelet aggregation than ADP. During the activation of platelets and coagulation cascade, ADP and thrombin are closely interrelated, and potentiate platelet aggregation and thrombus formation each other.
Source: CVD Prevention and Control - Category: Global & Universal Authors: Tags: Oral Abstract Source Type: research