Biologic mesh spacer placement facilitates safe delivery of dose-intense radiation therapy: A novel treatment option for unresectable liver tumors

The liver is a common site of metastasis for intra-abdominal malignancies [1]. Surgery continues to demonstrate better disease-free and overall survival for metastatic liver disease when technically feasible [2]. Liver directed therapies and systemic chemotherapy are utilized when resection is not possible with variable results [2]. There remain challenges when the liver lesions are too large, close to major vessels and when patient tolerance prohibits palliative chemotherapy. Traditionally, radiation therapy (RT) has not been considered a good option for the treatment of liver metastases due to the liver's poor tolerance to radiation and the risk of radiation-induced liver disease (RILD) [3].
Source: Surgical Oncology - Category: Surgery Authors: Source Type: research