Low CDX1 expression predicts a poor prognosis for hepatocellular carcinoma patients after hepatectomy

The caudal-type homeobox 1 (CDX1) transcription factor is a member of the caudal-related homeobox transcription factor gene family and has been reported to be down-regulated in a variety of cancers. However, the expression status and significance of CDX1 in hepatocellular carcinoma (HCC) is still controversial, and little is known about the role of CDX1 in HCC ·In our previous study, we investigated the expression and clinical significance of CDX1 in HCC samples from 313 HCC patients. We found CDX1 was strikingly down-regulated in HCC samples.

Source: Surgical Oncology - May 23, 2016 Category: Surgery Authors: Hao Zheng, Yuan Yang, Meng-chao Wang, Sheng-xian Yuan, Tao Tian, Jun Han, Jun-sheng Ni, Jian Wang, Hao Xing, Wei-ping Zhou Source Type: research