Deregulation of microRNA-181c in cerebrospinal fluid of patients with clinically isolated syndrome is associated with early conversion to relapsing-remitting multiple sclerosis

Conclusions:
Cerebrospinal fluid miRNA-181c might serve as a biomarker for early conversion to RRMS. Moreover, our data suggest an intrathecal origin of microRNAs detected in the cerebrospinal fluid.

Source: Multiple Sclerosis - July 25, 2016 Category: Neurology Authors: Ahlbrecht, J., Martino, F., Pul, R., Skripuletz, T., Sühs, K.-W., Schauerte, C., Yildiz, O., Trebst, C., Tasto, L., Thum, S., Pfanne, A., Roesler, R., Lauda, F., Hecker, M., Zettl, U. K., Tumani, H., Thum, T., Stangel, M. Tags: July 2016 22 (8) Original Research Papers Source Type: research