Cutaneous manifestations and management of hematologic neoplasms

Many malignant hematologic neoplasms can directly and indirectly involve the skin with lesions that are disfiguring, painful, and compromise integumentary function. The majority of lymphomas that directly infiltrate the skin are of T-cell origin but B-cell lymphomas, and other hematologic neoplasms, including acute myeloid and lymphoblastic leukemias, can also have cutaneous involvement, whereas some have an indolent course, eg, mycosis fungoides and marginal zone lymphoma, and easily respond to localized therapy with overall survival (OS) measured in years to decades.

Source: Seminars in Oncology - February 21, 2016 Category: Cancer & Oncology Authors: Olalekan O. Oluwole, John A. Zic, Jonathan J. Douds, Mary Ann Thompson, John P. Greer Source Type: research