Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis

This study indicates that additional genetic changes, such as 20q11.2 gain, which encodes the E2F1 gene, can be acquired through clonal evolution, and may be required for the metastatic process. This article is protected by copyright. All rights reserved.

Source: Genes, Chromosomes and Cancer - July 27, 2016 Category: Cancer & Oncology Authors: Takuma Morita, Narikazu Uzawa, Kaoru Mogushi, Jun Sumino, Chieko Michikawa, Ken ‐Ichiro Takahashi, Kunihiro Myo, Toshiyuki Izumo, Kiyoshi Harada Tags: Research Article Source Type: research