Combinatorial antibody libraries: new advances, new immunological insights

Nature Reviews Immunology 16, 498 (2016). doi:10.1038/nri.2016.67 Author: Richard A. Lerner Immunochemists have become quite proficient in engineering existing antibody molecules to control their pharmacological properties. However, in terms of generating new antibodies, the combinatorial antibody library has become a central feature of modern immunochemistry. These libraries are essentially an immune system in a test tube
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research