Innate sensing of oxidation-specific epitopes in health and disease

Nature Reviews Immunology 16, 485 (2016). doi:10.1038/nri.2016.63 Authors: Christoph J. Binder, Nikolina Papac-Milicevic & Joseph L. Witztum Ageing, infections and inflammation result in oxidative stress that can irreversibly damage cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of these deleterious consequences that not only alters lipid function but also leads to the formation of neo-self epitopes —
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research