The unfolded protein response in immunity and inflammation

Nature Reviews Immunology 16, 469 (2016). doi:10.1038/nri.2016.62 Authors: Joep Grootjans, Arthur Kaser, Randal J. Kaufman & Richard S. Blumberg The unfolded protein response (UPR) is a highly conserved pathway that allows the cell to manage endoplasmic reticulum (ER) stress that is imposed by the secretory demands associated with environmental forces. In this role, the UPR has increasingly been shown to have crucial functions in
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research