Asymptomatic elevated total serum bile acids representing an unusual form of intrahepatic cholestasis of pregnancy

Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-related liver disorder. ICP is associated with several high-risk adverse perinatal outcomes including meconium-stained amniotic fluid, fetal compromise, and stillbirth [1,2]. ICP is diagnosed by the occurrence of unexplained pruritus and increased serum bile acids, and usually occurs in the late second trimester or third trimester of pregnancy. In fact, pruritus during pregnancy is one of the initial hallmarks of ICP. The incidence of ICP in Si Chuan, China, is between 3% and 8.3%, and is higher than in other regions of China [3].
Source: International Journal of Gynaecology and Obstetrics - Category: OBGYN Authors: Tags: Brief communication Source Type: research