Prediction of promiscuous T-Cell epitopes in the Zika Virus polyprotein: An in silico approach

Conclusion The predicted conserved promiscuous T-cell epitopes examined in this study were reported for the first time and will contribute to the imminent design of Zika virus vaccine candidates, which will be able to induce a broad range of immune responses in a heterogeneous HLA population. However, our results can be verified and employed in future efficacious vaccine formulations only after successful experimental studies.
Source: Asian Pacific Journal of Tropical Medicine - Category: Tropical Medicine Source Type: research