The genetics and mechanisms of T cell acute lymphoblastic leukaemia

Nature Reviews Cancer 16, 494 (2016). doi:10.1038/nrc.2016.63 Authors: Laura Belver & Adolfo Ferrando T cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy derived from early T cell progenitors. In recent years genomic and transcriptomic studies have uncovered major oncogenic and tumour suppressor pathways involved in T-ALL transformation and identified distinct biological groups associated with prognosis. An
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research