Tumour suppressors: The dark side of p21

Nature Reviews Cancer 16, 481 (2016). doi:10.1038/nrc.2016.78 Author: Eytan Zlotorynski Whereas activation of p21 by p53 causes G1 cell cycle arrest, p53-independent expression of p21 can cause deregulation of DNA replication and genomic instability.

http://feeds.nature.com/~r/nrc/rss/current/~3/vRCxWsnbK2Y/nrc.2016.78

Source: Nature Reviews Cancer - July 14, 2016 Category: Cancer & Oncology Authors: Eytan Zlotorynski Tags: Research Highlight Source Type: research

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