Cancer ‐specific promoters for expression‐targeted gene therapy: ran, brms1 and mcm5

ConclusionsThe ran, brms1, and mcm5 promoters have the specificity and strength needed for cancer‐specific expression‐targeted gene therapy. pran in particular produced exciting results when coupled with a version of the caspase 3 exon to treat bladder cancer. Copyright © 2016 John Wiley & Sons, Ltd.

Source: The Journal of Gene Medicine - July 4, 2016 Category: Genetics & Stem Cells Authors: Xuguang Chen, Jacqueline E. Scapa, David X. Liu, W T. Godbey Tags: Research Article Source Type: research