Oncolytic vaccinia virus inhibits human hepatocellular carcinoma MHCC97 ‐H cell proliferation via endoplasmic reticulum stress, autophagy and Wnt pathways

ConclusionsOur results may provide new insight into the mechanisms of VV‐induced tumor cell death. The engineered recombinant VV containing optimized therapeutic transgenes may provide a new avenue for cancer gene therapy.

Source: The Journal of Gene Medicine - June 30, 2016 Category: Genetics & Stem Cells Authors: Xiaoyuan Jia, Yongyi Chen, Xin Zhao, Chunwei Lv, Jie Yan Tags: Research Article Source Type: research