A novel HLA ‐B*40 allele, B*40:01:40, identified in a Chinese individual

Summary
A new allele, officially named B*40:01:40, was detected in a Chinese individual by sequence‐based typing (SBT). The new allele differs from B*40:01:01 by a single nucleotide exchange at position 99 in codon 9, which results in synonymous substitution and seems not to compromise the HLA complex and T‐cell receptor interaction.

Source: International Journal of Immunogenetics - June 14, 2016 Category: Genetics & Stem Cells Authors: Y. F. Pei, H. N. Huang, H. C. Li, W. D. Shen Tags: Short Communication Source Type: research