Effect of Neutral-pH, Low –Glucose Degradation Product Peritoneal Dialysis Solutions on Residual Renal Function, Urine Volume, and Ultrafiltration: A Systematic Review and Meta-Analysis

This meta-analysis of eleven trials of 643 patients used a random effects model to evaluate the effect of peritoneal dialysate with neutral-pH, low-glucose degradation products on residual renalfunction, urine volume, peritoneal ultrafiltration, and peritoneal small-solute transport (dialysate to plasma creatinine ratio).  The results show a positive effect on preservation of residual renal function and greater urine volumes only.  However, the authors rightly conclude more studies are needed to determine the effect of these more costly solutions on harder clinical outcomes. : Effect of Low Versus High Dialysate Sodium Concentration on Blood Pressure and Endothelial-Derived Vasoregulators During Hemodialysis: A Randomized Crossover Study. Peritoneal Equilibration Test and Patient Outcomes. The time course of peritoneal transport parameters in peritoneal dialysis patients who develop encapsulating peritoneal sclerosis.
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Clinical Nephrology Peritoneal Dialysis Residual Renal Function Source Type: research