Blood concentration of prilocaine and lidocaine after the use of topical anesthesia (Oraqix ®) in lacerated wounds

ConclusionWhen Oraqix® was applied directly into the skin laceration, the plasma concentration of lidocaine and prilocaine was significantly increased as compared to when applied on intact skin. The present study, albeit in mice, indicates that the plasma levels of lidocaine and prilocaine can reach very high levels when the thermosetting gel Oraqix® is placed directly in wounds.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fedt.12294

Source: Dental Traumatology - July 9, 2016 Category: Dentistry Authors: Ala Al ‐Musawi, Kamal Matar, Samuel Kombian, Lars Andersson Tags: Original Article Source Type: research