Single Intradiscal Administration of the Tumor Necrosis Factor ‐Alpha Inhibitor, Etanercept, for Patients with Discogenic Low Back Pain

ConclusionsSingle intradiscal administration of a TNF‐α inhibitor can alleviate intractable discogenic LBP for up to 8 weeks. TNF‐α may be involved in discogenic pain pathogenesis. This procedure is a novel potential treatment; longer‐term effectiveness trials are required in the future.

Source: Pain Medicine - August 3, 2015 Category: Anesthesiology Authors: Takeshi Sainoh, Sumihisa Orita, Masayuki Miyagi, Gen Inoue, Hiroto Kamoda, Tetsuhiro Ishikawa, Kazuyo Yamauchi, Miyako Suzuki, Yoshihiro Sakuma, Go Kubota, Yasuhiro Oikawa, Kazuhide Inage, Jun Sato, Yukio Nakata, Junichi Nakamura, Yasuchika Aoki, Tomoaki Tags: Original Source Type: research