Chaperoning SNARE assembly and disassembly

Nature Reviews Molecular Cell Biology 17, 465 (2016). doi:10.1038/nrm.2016.65 Authors: Richard W. Baker & Frederick M. Hughson Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). However, the assembly of such complexes in vitro is inefficient, and their uncatalysed disassembly is undetectably slow. Here, we focus on the cellular machinery
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research