Nuclear organization: Building nuclear bodies with RNA

Nature Reviews Molecular Cell Biology 17, 463 (2016). doi:10.1038/nrm.2016.102 Author: Katharine H. Wrighton Several long non-coding RNAs function as scaffolds in the construction of nuclear bodies. Mannen et al. sought novel nuclear bodies containing such 'architectural RNA' (arcRNA). The proteins DBC1, HNRNPD, HNRNPL, ZNF346 and SAM68 localized to SAM68 nuclear bodies (SNBs). SNBs disappeared in the presence
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research