Nuclear organization: Building nuclear bodies with RNA
Nature Reviews Molecular Cell Biology 17, 463 (2016).
doi:10.1038/nrm.2016.102
Author: Katharine H. Wrighton
Several long non-coding RNAs function as scaffolds in the construction of nuclear bodies. Mannen et al. sought novel nuclear bodies containing such 'architectural RNA' (arcRNA). The proteins DBC1, HNRNPD, HNRNPL, ZNF346 and SAM68 localized to SAM68 nuclear bodies (SNBs). SNBs disappeared in the presence
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Katharine H. Wrighton Tags: Research Highlight Source Type: research