Gene expression: Promoters as spiked enhancers

Nature Reviews Molecular Cell Biology 17, 463 (2016). doi:10.1038/nrm.2016.101 Author: Eytan Zlotorynski Sequence determinants that distinguish between promoter and enhancer activities are poorly characterized. Nguyen et al. used massive parallel promoter and enhancer reporter assays in mouse cortical neurons to examine the activities of multiple short (139 bp) sequences that cover hundreds of conserved promoters and
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research