Protein translocation: Channelling the route for ER misfolded proteins

Nature Reviews Molecular Cell Biology 17, 462 (2016). doi:10.1038/nrm.2016.92 Author: Paulina Strzyz Hrd1 may form a channel regulated by autoubiquitylation that has a major role in translocating misfolded proteins from the ER lumen to the cytoplasm for subsequent degradation.
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research