Cancer biology: The dark side of p21
Nature Reviews Molecular Cell Biology 17, 461 (2016).
doi:10.1038/nrm.2016.90
Author: Eytan Zlotorynski
Whereas activation of p21 by p53 causes G1 cell cycle arrest, p53-independent expression of p21 can cause deregulation of DNA replication and genomic instability.
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Eytan Zlotorynski Tags: Research Highlight Source Type: research