In utero exposure to venlafaxine, a serotonin –norepinephrine reuptake inhibitor, increases cardiac anomalies and alters placental and heart serotonin signaling in the rat

ConclusionIn utero venlafaxine exposure altered the placental index and induced fetal cardiac anomalies in rats. We propose that the increased incidence of cardiac anomalies is mediated through alterations in serotonin signaling in the placenta and fetal heart. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 6, 2016 Category: Perinatology & Neonatology Authors: Laetitia Laurent, Chunwei Huang, Sheila R. Ernest, Anick Berard, Cathy Vaillancourt, Barbara F. Hales Tags: Original Research Article Source Type: research